Publication Details: UM-CS-2008-034

Drug Addiction: a Computational Multiscale Model Combining Neuropsychology, Cognition, and Behavior.

Publication Type:Technical Report
Author(s):Y. Z. Levy, D. Levy, J. Meyer, H. T. Siegelmann
Abstract:According to the United Nations, approximately 24.7 million people used amphetamines, 16 million used cocaine, and 12 million used heroin in 2006/07. Full recovery from drug addiction by chemical treatment and/or social and psychological support is uncertain. The present investigation was undertaken to expand our understanding of the factors that drive the dynamics of addiction. A new multiscale computational model is presented which integrates current theories of addiction, unlike previous models, considers addiction as a reversible process. Explicit time dependency is added to the inhibition and the compulsion processes. Preliminary computational predictions of drug-seeking behavior are presented and potential correlation with experimental data is discussed. Validation of the model appears promising, however additional investigation is required.